Edit |   |
Antigenic Specificity | Phospho-VE-Cadherin (Tyr731) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-VE-Cadherin (Tyr731) antibody detects endogenous levels of VE-Cadherin only when phosphorylated at Tyrosine 731. Description: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular ju |
Immunogen | Immunogen: A synthesized peptide derived from human VE-Cadherin around the phosphorylation site of Tyrosine 731 Subcellular Location: Cell Junction. Cell Membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries. Tissue Specificity: Endothelial tissues and brain. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken Similarity: Pig (83%), Zebrafish (92%), Bovine (92%), Horse (100%), Sheep (88%), Dog (92%), Chicken (92%) |
Other Names | [7B 4; 7B4; 7B4 antigen; CADH5_HUMAN; Cadherin 5; Cadherin 5 type 2; Cadherin 5, type 2 (vascular endothelium); Cadherin 5, type 2, VE cadherin (vascular epithelium); cadherin, vascular endothelial; cadherin, vascular endothelial, 1; Cadherin-5; Cadherin5; CD 144; CD144; CD144 antigen; CDH 5; CDH5; CDH5 protein; Endothelial specific cadherin; FLJ17376; OTTHUMP00000174777; Vascular endothelial cadherin; Vascular epithelium cadherin; VE Cad; VE-cadherin; VEC] |
Gene, Accession # | [CDH5], Gene ID: 1003, NCBI: NP_001786.2, UniProt: P33151 |
Catalog # | MBS9601036 |
Price | $240, $280 |
Order / More Info | Phospho-VE-Cadherin (Tyr731) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |