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Antigenic Specificity | Bax |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bax Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bax, a pro-apoptotic Bcl-2 family member, is a cytosolic protein that changes conformation and translocates to the mitochondria following apoptotic stimuli. It is thought to share significant functional homology with Bak, another pro-apoptotic Bcl-2 family member, as disruption of bax or bak has little effect on cell death, but mice lacking both genes dis |
Immunogen | Immunogen: Bax antibody was raised against a peptide corresponding to 16 amino acids near the amino-terminus of human Bax. Buffer: Bax Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Bax; BCL2L4; BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BCL2-associated X protein], [BAX; BAX; BCL2L4; BCL2L4; Bcl2-L-4] |
Gene, Accession # | [BAX], Gene ID: 581, NCBI: AAA03619, UniProt: Q07812 |
Catalog # | MBS151240 |
Price | $375 |
Order / More Info | Bax Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |