beta-Catenin (p120) Antibody from MYBIOSOURCE INC.

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Antigenic Specificitybeta-Catenin (p120)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
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DescriptionSpecificity: Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex. In breast ductal neoplasia, beta-catenin is usually localized in cellular membranes. However, in lobular neoplasia, a marked redistribution of beta-catenin throughout the cytoplasm results in a diffuse cytoplasmic pattern. Immuno-staining of beta-catenin and E-cadherin is helps in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Additionally, som
ImmunogenImmunogen: A synthetic peptide from the middle of beta-Catenin (p120) protein
Other Names[Cadherin associated protein), beta 1 88kDa, Catenin beta-1, CATNB, CHBCAT, CTNNB1], [CTNNB1; CTNNB1; CTNNB; MRD19; armadillo; CTNNB]
Gene, Accession #[CTNNB1], Gene ID: 1499, NCBI: NP_001091679.1, UniProt: P35222
Catalog #MBS438217
Price$190, $340, $340
Order / More Infobeta-Catenin (p120) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesDabbs DJ et. al. Am J Surg Path. 2007;31:427-437. Sarrio D et. al. Oncogene. 2004;23:3272-3283. Mastracci TL et. al. Mod Path. 2005;18:741-751
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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