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Antigenic Specificity | Mouse CD289 (N-TERMINAL) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 2.0mg/ml |
Applications | Immunohistology Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goat anti Mouse CD289 antibody recognises murine Toll-like receptor 9, also known as CD289 or TLR9. CD289 is an 1032 amino acid ~120 kDa endosomal single pass type I transmembrane glycoprotein with a number of leucine rich repeats and a single TIR domain (UniProt: Q9NR96). Goat anti Mouse CD289 antibody recognizes an epitope within the N-terminal (NT) region of CD289, a member of the toll-like receptor family, which triggers MyD88 and TRAF6, resulting in NF-kappaB activation, cytokine secretion and the inflammatory response. CD289 acts as a receptor for unmethylated cytidine-phosphate-guanosine dinucleotides in bacterial DNA (CpG-DNA), playing a primary role in pathogen recognition and activation of innate immunity andhas been shown to play |
Immunogen | Histology Positive Control Tissue: Spleen, thymus or tonsil Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to mouse CD289 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Mouse |
Other Names | [toll-like receptor 9; Toll-like receptor 9; toll-like receptor 9; toll-like receptor 9; CD_antigen: CD289], [TLR9; TLR9; CD289] |
Gene, Accession # | [CD289], Gene ID: 54106, NCBI: NP_059138.1 |
Catalog # | MBS224156 |
Price | $470 |
Order / More Info | Mouse CD289 (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |