RIP3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRIP3
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration500 ug/ml
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionReceptor interacting protein including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3. RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the c-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, and mediates TNF-R1 mediated apoptosis, and attenuates RIP and TNFR1 induced NFkB activation. Overexpression of RIP3 induces apoptosis and NFkB activation.
ImmunogenImmunogen: RIP3 antibody was raised in Rabbit using synthetic peptide corresponding to residues surrounding amino acid 476 of mouse RIP3 as the immunogen.
Other Names[Rabbit RIP3; RIP3; RIP3; RIP like protein kinase 3; RIP-3; RIP3; RIP 3; RIPK3; RIP 3; RIPK3; RIP-3]
Gene, Accession #[RIP3]
Catalog #MBS5311253
Price$490
Order / More InfoRIP3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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