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Antigenic Specificity | RIP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor interacting protein including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3. RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the c-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, and mediates TNF-R1 mediated apoptosis, and attenuates RIP and TNFR1 induced NFkB activation. Overexpression of RIP3 induces apoptosis and NFkB activation. |
Immunogen | Immunogen: RIP3 antibody was raised in Rabbit using synthetic peptide corresponding to residues surrounding amino acid 476 of mouse RIP3 as the immunogen. |
Other Names | [Rabbit RIP3; RIP3; RIP3; RIP like protein kinase 3; RIP-3; RIP3; RIP 3; RIPK3; RIP 3; RIPK3; RIP-3] |
Gene, Accession # | [RIP3] |
Catalog # | MBS5311253 |
Price | $490 |
Order / More Info | RIP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |