Edit |   |
---|---|
Antigenic Specificity | CAPS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Numerous isoforms of CAPS1 are known to exist. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2. CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4, 5-bisphosphate and is thought to be a specific regulato |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 21 amino acid peptide near the amino terminus of the human CAPS1. |
Other Names | [Calcium-dependent secretion activator 1, CADPS1] |
Gene, Accession # | [CAPS1], Gene ID: 8618, NCBI: NP_899631 |
Catalog # | MBS9401432 |
Price | $320 |
Order / More Info | CAPS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |