GRP78 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGRP78
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.1 mL
Concentration100ug/100ul
ApplicationsPeptide ELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: GRP78 Bip antibody detects endogenous levels of GRP78 Bip protein. Not tested with other proteins. When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]
ImmunogenImmunogen: Synthetic peptide conjugated to KLH
Other Names[GRP78 Bip], [HSPA5; HSPA5; BIP; MIF2; GRP78; HEL-S-89n]
Gene, Accession #[GRP78], Gene ID: 3309, NCBI: AAA52614.1
Catalog #MBS415427
Price$230
Order / More InfoGRP78 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHegde,N.R., Chevalier,M.S., Wisner,T.W et,al The role of BiP in endoplasmic reticulum-associated degradation of major histocompatibility complex class I heavy chain induced by cytomegalovirus proteins
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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