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Antigenic Specificity | Human HLA B27 |
Clone | [HLA-ABC-m3] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2a |
Format | fluorescein (FITC) conjugate |
Size | 100 tests |
Concentration | Approximate Protein concentration: 50 ug/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human HLA B27 antibody, clone HLA-ABC-m3 recognizes the HLA-B27 alloantigen. This antibody reacts with the peripheral blood lymphocytes of 47/47 individuals conventionally typed as HLA-B27 + and precipitates cell surface molecules of 43 and 12 kD, corresponding to the HLA Class 1 heavy chain and beta 2 microglobulin. Affinity studies by Scatchard analysis showed that this antibody has a higher affinity for HLA-B27 (9.7 x 108M-1) than for HLA B7 (9.5 x 107 M-1). Subjects Expected Fluorescence Intensity Heterozygous HLA-B27+ Strong Homozygous HLA-B27+ Strong Heterozygous HLA-B7+ Faint Non B27, Non B7 Negative |
Immunogen | Immunogen: Immune complex precipitated from HLA-B27 positive cell line (Bordin) by anti HLA-antibody and Staphylococcal Protein A. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [HLA class I histocompatibility antigen, B-27 alpha chain; HLA class I histocompatibility antigen, B-27 alpha chain; major histocompatibility complex, class I, B; HLA class I histocompatibility antigen, B alpha chain; MHC Class I HLA heavy chain; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; MHC class I antigen GN00104; MHC class I antigen HLA-B heavy chain; MHC class I antigen SHCHA; leukocyte antigen class I-B; lymphocyte antigen; major histocompatibility complex, class I, B; MHC class I antigen B*27], [HLA-B; HLA-B; AS; HLAB; SPDA1; HLAB] |
Gene, Accession # | [HLA B27], Gene ID: 3106, NCBI: P03989.2, UniProt: P03989 |
Catalog # | MBS210626 |
Price | $370 |
Order / More Info | Human HLA B27 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |