Robo1 (C-Terminal Region) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Robo1 (C-Terminal Region) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was affinity purified using Robo1 (C-terminal region) peptide. The purified antibody detects a 180 kDa* band corresponding to Robo1 in Western blots of human HepG2 and HUVEC cells, as well as mouse C2C12 cells. The Robo family of repulsive guidance receptors (Robo1-4) have important roles in controlling axon guidance and cell migration. These receptors are members of the immunoglobulin (Ig) superfamily and consist of an ectodomain with five Ig domains and three fibronectin type III repeats, a single transmembrane domain, and a long cytoplasmic tail that contains four blocks of conserved cytoplasmic sequences. In Drosophila, mutations in Robo, and its midline-expressed ligand Slit, result in too many axons crossing and staying |
| Immunogen | Immunogen: Robo1 synthetic peptide (coupled to carrier protein) corresponds to amino acids in the C-terminal region of human Robo1. This sequence has significant homology to the same region in rat and mouse Robo1, and has low homology to other Robo family members. |
| Other Names | [roundabout; DUTT1], [ROBO1; ROBO1; SAX3; DUTT1; DUTT1] |
| Gene, Accession # | [Robo1], Gene ID: 6091, NCBI: NP_002932.1, UniProt: Q9Y6N7 |
| Catalog # | MBS474134 |
| Price | $325 |
| Order / More Info | Robo1 (C-Terminal Region) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kidd, T. et al. (1998) Cell 92:205.Bashaw, G.J. et al. (2000). Cell 101:703.Yang, L. & Bashaw, G.J. (2006). Neuron 52:595. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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