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Antigenic Specificity | HSPA5 (C-term), 541-568 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, porcine, rat, Xenopus) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.48 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HSPA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-568 amino acids from the C-terminal region of human HSPA5. When Chinese hamster K12 cells are starved of glucose, thesynthesis of several proteins, called glucose-regulated proteins(GRPs), is markedly increased. Hendershot et al. (1994) [PubMed8020977] pointed out that one of these, GRP78 (HSPA5), alsoreferred to as 'immunoglobulin heavy chain-binding protein' (BiP),is a member of the heat-shock protein-70 (HSP70) family and isinvolved in the folding and assembly of proteins in the endoplasmicreticulum (ER). Because so many ER proteins interact transientlywith GRP78, it may play a key role in monitoring |
Immunogen | n/a |
Other Names | [78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP; HSPA5; GRP78] |
Gene, Accession # | [HSPA5], Gene ID: 3309, NCBI: NP_005338.1, UniProt: P11021 |
Catalog # | MBS9211383 |
Price | $165, $370 |
Order / More Info | HSPA5 (C-term), 541-568 Antibody from MYBIOSOURCE INC. |
Product Specific References | Zhao, C., et al. J. Med. Virol. 82(1):14-22(2010) Zhuang, L., et al. Mod. Pathol. 23(1):45-53(2010) Arnaudeau, S., et al. Proteomics 9(23):5316-5327(2009) |