Occludin (Marker of Early Blood Brain Barrier Damage) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityOccludin (Marker of Early Blood Brain Barrier Damage)
Clone[OCLN/2181]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of Occludin. Expression of Occludin is upregulated by polyunsaturated fatty acids, increasing trans-endothelial cell resistance and reducing cellular permeability to large molecules. The level of Occludin varies greatly depending on tissue; in brain tissue, Occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Occludin is a tight junction protein that is a key structu
ImmunogenImmunogen: Recombinant fragment of human Occludin protein (around aa 282-415) (exact sequence is proprietary)
Other Names[BLCPMG; Occludin; OCLN; Phosphatase 1 regulatory subunit 115; PTORCH1; Tight junction protein occludin]
Gene, Accession #[OCLN], Gene ID: 100506658, NCBI: NP_001192184.1, UniProt: Q16625
Catalog #MBS4380766
Price$190, $340, $340
Order / More InfoOccludin (Marker of Early Blood Brain Barrier Damage) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesPan, R. et al. Blood Occludin Level as a Potential Biomarker for Early Blood Brain Barrier Damage Following Ischemic Stroke. Sci. Rep. 7, 40331; (2017)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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