BCAR3 (phospho) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | BCAR3 (phospho) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes phosphorylated Threonin 130 of human BCAR3 protein. It does not recognize the nonphosphorylated BCAR3. Breast cancer anti-estrogen resistance 3 (BCAR3) is a also known as AND-34/BCAR3/NSP2 (BCAR3). Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. BCAR3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellula |
| Immunogen | n/a |
| Other Names | [breast cancer estrogen resistance 3], [BCAR3; BCAR3; NSP2; SH2D3B; NSP2; SH2D3B] |
| Gene, Accession # | [BCAR3], Gene ID: 8412, NCBI: NP_001248339.1, UniProt: O75815 |
| Catalog # | MBS460313 |
| Price | $285 |
| Order / More Info | BCAR3 (phospho) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Makkinje, A., et al. AND-34/BCAR3 regulates adhesion-dependent p130cas serine phosphorylation and breast cancer cell growth pattern. Cell. Signal. 21 (9), 1423-1435 (2009). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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