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Antigenic Specificity | PICK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total PICK1 protein. Protein interacting with C kinase 1 (PICK1) is a PDZ-domain containing protein that is located in the perinuclear region and is phosphorylated in response to PKC activation. PKC , which is essential for the regulation of proliferation and differentiation in numerous cell types, contains within its catalytic region a PDZ-binding domain that is absent from other PKC isoforms. Mutation of the PICK1 PDZ domain inhibits the binding of PICK1 to PKC. PICK1 also interacts with the carboxy terminus of a-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor, a neurotransmitter receptor located at excitatory synapses, suggesting that PICK1 plays a role in the modulation of syn |
Immunogen | Immunogen Type: Peptide Immunogen Description: A synthetic peptide of human PICK1. |
Other Names | [MGC15204; PICK; PRKCABP] |
Gene, Accession # | [PICK1], Gene ID: 9463, NCBI: NP_001034672.1, UniProt: Q9NRD5 |
Catalog # | MBS9408250 |
Price | $255 |
Order / More Info | PICK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |