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Antigenic Specificity | TSLP Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells; co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal tra |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 19 amino acid peptide from near the center of human TSLP receptor. |
Other Names | [TSLP Receptor, Thymic stromal lymphopoietin receptor] |
Gene, Accession # | [TSLP], Gene ID: 64109, NCBI: NP_001012288.2, UniProt: Q9HC73 |
Catalog # | MBS9408813 |
Price | $320 |
Order / More Info | TSLP Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |