Tyrosine Hydroxylase (Ab-31) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTyrosine Hydroxylase (Ab-31)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total Tyrosine Hydroxylase protein. Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the synthesis of the neurotransmitter dopamine and other catecholamines. TH functions as a tetramer, with each subunit composed of a regulatory and catalytic domain, and exists in several different isoforms. This enzyme is required for embryonic development since TH knockout mice die before or at birth. Levels of transcription, translation and posttranslational modification regulate TH activity. The amino-terminal regulatory domain contains three serine residues: Ser9, Ser31 and Ser40. Phosphorylation at Ser40 by PKA positively regulates the catalytic activity of TH. Phosphorylation at Ser31 by CDK5 als
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.29~33(V-T-S-P-R)derived from Mouse Tyrosine Hydroxylase.
Other Names[TYH; DYT14; DYT5b; TH]
Gene, Accession #Gene ID: 7054, NCBI: NP_000351.2, UniProt: P07101
Catalog #MBS9408999
Price$200, $255
Order / More InfoTyrosine Hydroxylase (Ab-31) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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