PFN1 (C-term) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PFN1 (C-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PFN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 87-120 amino acids from the C-terminal region of human PFN1. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR. |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); Profilin-1; Epididymis tissue protein Li 184a; Profilin I; PFN1] |
| Gene, Accession # | [PFN1], Gene ID: 5216, NCBI: NP_005013.1, UniProt: P07737 |
| Catalog # | MBS9216026 |
| Price | $150 |
| Order / More Info | PFN1 (C-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kwiatkowski D.J.,et al.J. Biol. Chem. 263:5910-5915(1988).Li J.,et al.Mol. Cell. Proteomics 9:2517-2528(2010).Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.Ota T.,et al.Nat. Genet. 36:40-45(2004).Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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