IRS-2 (Paired S731) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIRS-2 (Paired S731)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsELISA, Western Blot, Immunohistochemistry
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DescriptionThis antibody recognizes ~180 kDa of human IRS-2. It also reacts with mouse and rat. The other species are not tested. Insulin Receptor Substrate-2 (IRS-2), a 180kDa cytoplasmic docking protein, is one of the major endogenous substrates of the insulin receptor kinase. The insulin receptor mediates insulin action through the phosphorylation of substrate proteins. The major substrates of the insulin receptor kinase are the insulin receptor substrate (IRS) family of proteins, IRS 1, IRS 2, IRS 3, and IRS 4. IRS 2, a signaling molecule that mediates effects of insulin, Insulin-like growth factor 1 and other cytokines by acting as a molecular adaptor between diverse receptor kinases and downstream effectors. IRS proteins contain more than 70 pot
ImmunogenAntigen Preparation: A synthetic peptide corresponding to the epitope ASSPA without phosphorylation site Ser 731 of human IRS-2.
Other Names[Rabbit IRS-2 (Paired731); Insulin-receptor substrate 2 (IRS-2).], [IRS2; IRS2; IRS-2]
Gene, Accession #[IRS-2 (Paired S731)], Gene ID: 8660, NCBI: NP_003740.2, UniProt: Q96RG4
Catalog #MBS462063
Price$285
Order / More InfoIRS-2 (Paired S731) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLi, Y. et al. (2004) J. Biol. Chem. 279, 45304-45307.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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