MERTK Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | MERTK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 0.75 ug/ul in antibody stabilization buffer |
| Applications | Confocal Microscopy (CM), ELISA (EIA), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Affinity Purified Human cellular proto-oncogene (c-mer) mRNA Antibody C-epitope. Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. MERTK signaling plays a role in various processes such as macrophage c |
| Immunogen | Immunogen: Synthetic peptide taken within amino acid region 900-994 on MerTK protein. Immunoglobulin: IgG. Expression: Is expressed in many neoplastic B- and T-cells. Is expressed highly in testis, ovary, prostate, lung and kidney and is expressed at low levels in the spleen, small intestine, colon and liver. |
| Other Names | [c MER; c mer proto oncogene tyrosine kinase; Eyk; MER; MER receptor tyrosine kinase; MERK; MERPEN; Mertk; MERTK c-mer proto-oncogene tyrosine kinase; MGC133349; nmf12; Nyk; Proto oncogene tyrosine protein kinase MER; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; RP38; STK kinase; Tyrosine-protein kinase Mer], [Mertk; Mertk; rdy; Mer] |
| Gene, Accession # | [MERTK], Gene ID: 65037, NCBI: NP_075232, UniProt: Q12866 |
| Catalog # | MBS540377 |
| Price | $425 |
| Order / More Info | MERTK Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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