Mouse CD80 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD80 |
| Clone | [RM80] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.25 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Immunohistology Frozen, Flow cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rat anti Mouse CD80 antibody, clone RM80 recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses. |
| Immunogen | Immunogen: BCL1 cells expressing CD80 Fusion Partners: Spleen cells from immunised SD rats were fused with cells of the P3U1 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
| Other Names | [T-lymphocyte activation antigen CD80; T-lymphocyte activation antigen CD80; T-lymphocyte activation antigen CD80; B7 protein; activation B7-1 antigen; CD80 antigen; Activation B7-1 antigen; B7; CD_antigen: CD80], [Cd80; Cd80; B71; Ly53; TSA1; Cd28l; Ly-53; MIC17; B7; B7] |
| Gene, Accession # | [CD80], Gene ID: 12519, NCBI: NP_033985.3, UniProt: Q00609 |
| Catalog # | MBS214314 |
| Price | $430 |
| Order / More Info | Mouse CD80 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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