ITM2C (N-term), 27-55 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | ITM2C (N-term), 27-55 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: monkey) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.36 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ITM2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITM2C. Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity). |
| Immunogen | n/a |
| Other Names | [Integral membrane protein 2C; Cerebral protein 14; Transmembrane protein BRI3; CT-BRI3; ITM2C; BRI3] |
| Gene, Accession # | [ITM2C], Gene ID: 81618, NCBI: NP_001012532.1, UniProt: Q9NQX7 |
| Catalog # | MBS9201371 |
| Price | $165, $370 |
| Order / More Info | ITM2C (N-term), 27-55 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010) Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010) Matsuda, S., et al. J. Biol. Chem. 284(23):15815-15825(2009) Matsuda, S., et al. Mol Neurodegener 4, 41 (2009) : Gong, Y., et al. BMB Rep 41(4):287-293(2008) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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