Human C5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human C5 |
| Clone | [046-10.2.2 (10-04] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | ELISA (EIA), Functional Assays (FN), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item recognises secreted complement component 5 (C5), a 190kDa serine protease present in blood serum. It is composed of an 115kDa disulphide linked alpha-chain and a 75 kDa beta-chain. In addition to its role in complement, C5 is thought to be associated with inflammation, stimulating tumour necrosis factor alpha, interferon gamma mediated suppression of IL10 and IL12 production. . . C5 is activated via either the classical or the alternative complement pathway, by proteolytic cleavage of C5a from the N-terminal of the alpha-chain, by C5 convertase. C5a is an anaphylotoxin which mediates local inflammation. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and b |
| Immunogen | Immunogen: Purified human C5 Buffer Solution: Borate buffered saline Target Species: Human |
| Other Names | [complement C5 preproprotein; Complement C5; complement C5; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C5a anaphylatoxin; anaphylatoxin C5a analog; prepro-C5; complement component 5; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4Cleaved into the following 4 chains:Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain], [C5; C5; C5D; C5a; C5b; ECLZB; CPAMD4; CPAMD4] |
| Gene, Accession # | [C5], Gene ID: 727, NCBI: NP_001726.2, UniProt: P01031 |
| Catalog # | MBS212915 |
| Price | $530 |
| Order / More Info | Human C5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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