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Antigenic Specificity | PARL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.3 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total PARL protein. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human presenilin associated, rhomboid-like |
Other Names | [PSARL; PSARL1; RHBDS1; PRO2207; PSENIP2] |
Gene, Accession # | [PARL], Gene ID: 55486, NCBI: NP_001032728.1, UniProt: Q9H300 |
Catalog # | MBS9412177 |
Price | $255 |
Order / More Info | PARL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |