HPS5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HPS5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: HPS5 antibody detects endogenous levels of HPS5. Function: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins.Subunit Structure: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6. Interacts with HPS6 (PubMed:15030569, PubMed:25189619). Interacts with HPS3 (PubMed:15030569). May interact with all alpha-integrin chains that have an aromatic residue before the first lysine of the conserved KXGFFKR motif, including ITGA2, ITGA3, ITGA5 and ITGA6 (PubMed |
| Immunogen | Immunogen: A synthesized peptide derived from human HPS5. Subcellular Location: Cytosol Tissue Specificity: Widely expressed. Isoform 1:Highly expressed in lungs and testis. Isoform 2:Highly expressed in placenta, kidney, testis ovary, lung and thymus. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Zebrafish (90%), Bovine (91%), Horse (100%), Sheep (91%), Rabbit (100%), Dog (100%) |
| Other Names | [AIBP63; Alpha integrin binding protein 63; BLOC2S2; Hermansky Pudlak syndrome 5 protein; HPS5, biogenesis of lysosomal organelles complex 2 subunit 2; Ru2; Ruby eye protein 2 homolog] |
| Gene, Accession # | [HPS5], Gene ID: 11234, NCBI: NP_009147.3, UniProt: Q9UPZ3 |
| Catalog # | MBS9603509 |
| Price | $240, $280 |
| Order / More Info | HPS5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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