JHDM2a (N-term), 50-79 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityJHDM2a (N-term), 50-79
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis JHDM2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human JHDM2a. JHDM2a is a zinc finger protein that contains a jumonji domain. It is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. This protein preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. It is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, r
Immunogenn/a
Other Names[Lysine-specific demethylase 3A; 11411-; JmjC domain-containing histone demethylation protein 2A; Jumonji domain-containing protein 1A; KDM3A; JHDM2A; JMJD1; JMJD1A; KIAA0742; TSGA]
Gene, Accession #[KDM3A], Gene ID: 55818, NCBI: NP_001140160.1, UniProt: Q9Y4C1
Catalog #MBS9211051
Price$165, $370
Order / More InfoJHDM2a (N-term), 50-79 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWellmann,S., Biochem. Biophys. Res. Commun. 372 (4), 892-897 (2008) Yamane,K., Cell 125 (3), 483-495 (2006)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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