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Antigenic Specificity | JHDM2a (N-term), 50-79 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This JHDM2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human JHDM2a. JHDM2a is a zinc finger protein that contains a jumonji domain. It is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. This protein preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. It is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, r |
Immunogen | n/a |
Other Names | [Lysine-specific demethylase 3A; 11411-; JmjC domain-containing histone demethylation protein 2A; Jumonji domain-containing protein 1A; KDM3A; JHDM2A; JMJD1; JMJD1A; KIAA0742; TSGA] |
Gene, Accession # | [KDM3A], Gene ID: 55818, NCBI: NP_001140160.1, UniProt: Q9Y4C1 |
Catalog # | MBS9211051 |
Price | $165, $370 |
Order / More Info | JHDM2a (N-term), 50-79 Antibody from MYBIOSOURCE INC. |
Product Specific References | Wellmann,S., Biochem. Biophys. Res. Commun. 372 (4), 892-897 (2008) Yamane,K., Cell 125 (3), 483-495 (2006) |