GABA-B Receptor 1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGABA-B Receptor 1
Clone[S93A-49]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formatallophycocyanin (APC) conjugate
Size0.1 mg
Concentration1mg/mL
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionBackground Info: Detects ~115kDa. No cross-reactivity against GABA(Beta)R2. Scientific Background: GABA (gamma-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B) and GABA(C) receptor. The ionotropic GABA(A) and GABA(C) receptors are ligand-gated ion channels that produce fast inhibitory synaptic transmission. In contrast, the metabotropic GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission (1). Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 where GABA(B)R1 binds the ligand and GABA(B)R2 is the primary G protein contact site (2). Two isoforms of GABA(B)R1 have been cloned
Immunogenn/a
Other Names[GABA-B receptor 1; GABA-B-R1; GABR1_Human; Gamma aminobutyric acid receptor 1; GB1; GPRC3A], [Gabbr1; Gabbr1; GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; Gb1]
Gene, Accession #Gene ID: 81657, NCBI: NP_112290.2, UniProt: Q9Z0U4
Catalog #MBS800327
Price$435
Order / More InfoGABA-B Receptor 1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Jones K.A. et al. (2000) Neuropsychopharmacology 23: 2. Duthey B. et al. (2002) J Biol Chem. 277: 3236-41. 3. Kaupmann K. et al. (1997) Nature 386: 239-46.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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