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Antigenic Specificity | Girdin (Phospho Ser1417) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Girdin (S1417) Polyclonal Antibody detects endogenous levels of Girdin protein only when phosphorylated at S1417. CCDC88A (coiled-coil domain containing 88A) encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of CCDC88A and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively |
Immunogen | Immunogen: Synthesized peptide derived from human Girdin around the phosphorylation site of S1417 |
Other Names | [Rabbit Girdin (phospho Ser1417); CCDC88A; APE; KIAA1212; Girdin; Akt phosphorylation enhancer; APE; Coiled-coil domain-containing protein 88A; G alpha-interacting vesicle-associated protein; GIV; Girders of actin filament; Hook-related protein 1; HkRP1] |
Gene, Accession # | [GRDN], Gene ID: 55704, NCBI: NP_001129069.1, UniProt: Q3V6T2 |
Catalog # | MBS9706379 |
Price | $130, $220, $325 |
Order / More Info | Girdin (Phospho Ser1417) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |