Girdin (Phospho Ser1417) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGirdin (Phospho Ser1417)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: Phospho-Girdin (S1417) Polyclonal Antibody detects endogenous levels of Girdin protein only when phosphorylated at S1417. CCDC88A (coiled-coil domain containing 88A) encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of CCDC88A and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively
ImmunogenImmunogen: Synthesized peptide derived from human Girdin around the phosphorylation site of S1417
Other Names[Rabbit Girdin (phospho Ser1417); CCDC88A; APE; KIAA1212; Girdin; Akt phosphorylation enhancer; APE; Coiled-coil domain-containing protein 88A; G alpha-interacting vesicle-associated protein; GIV; Girders of actin filament; Hook-related protein 1; HkRP1]
Gene, Accession #[GRDN], Gene ID: 55704, NCBI: NP_001129069.1, UniProt: Q3V6T2
Catalog #MBS9706379
Price$130, $220, $325
Order / More InfoGirdin (Phospho Ser1417) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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