Human PRKCA / PKC-Alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman PRKCA / PKC-Alpha
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg
Concentration0.1 mg/ml
ApplicationsImmunohistochemistry (IHC - Paraffin), ELISA (EIA)
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DescriptionSpecificity: Amino acids 491 to 501 with pTHR497 of human PRKCA. Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, tumorigenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascade involving MAPK1/3 (ERK1/2) and RAP1GAP. Involved in cell proliferation and cell growth arrest by positive and negative regulation of the cell cycle. Can promote cell growth by phosphorylating and activating RAF1, which mediates the activation of the MAPK/ERK signa
ImmunogenImmunogen Description: Synthetic peptide from human PRKCA / PKC-Alpha.
Other Names[PRKCA / PKC-Alpha (phospho-Thr497) IHC-plus; PRKCA; Aging-associated gene 6; AAG6; Alpha PKC; PKC-A; Pkcalpha; Protein kinase C alpha type; PKC Alpha; PKC-alpha; PKCA; Protein kinase c alpha; Protein kinase C; alpha; Human PRKCA; PKC-Alpha], [PRKCA; PRKCA; AAG6; PKCA; PRKACA; PKC-alpha; PKCA; PRKACA; PKC-A; PKC-alpha]
Gene, Accession #[PRKCA], Gene ID: 5578, NCBI: NP_002728.1, UniProt: P17252
Catalog #MBS241041
Price$530
Order / More InfoHuman PRKCA / PKC-Alpha Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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