Human CD49b Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD49b
Clone[HAS-4]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a, kappa
Formatunconjugated
Size100 tests
Concentrationn/a
ApplicationsIdentification and enumeration of CD49b+ cells by Flow Cytometry, Immunoprecipitation
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DescriptionSpecificity: Human CD49b, Mr 200-210 kDa. CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin alpha2 chain. CD49b associates noncovalently with CD29, the integrin beta1 subunit, to form the heterodimer integrin a2b1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts and long-term cultured T cells. CD49b/CD29 mediates the Mg++- dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during would healing.
Immunogenn/a
Other Namesn/a
Gene, Accession #NCBI: ADM15550.1
Catalog #MBS670272
Price$260
Order / More InfoHuman CD49b Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBarclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD49b Section, Academic Press, New York, p. 257.Favaloro, E. J., et al. 1990. Br. J. Haem. 74:385.Mazurov, A. V., et al. 1991. Thromb. Haemost. 66:494.Hemler, M.E. 1990. Annu. Rev. Immunol. 114:365.Takada, Y., and M.E. Hemler. 1989. J. Cell. Biol. 109:397.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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