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Antigenic Specificity | CK16 |
Clone | [6F6] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The CK16 Mouse Monoclonal antibody detects endogenous CK16 proteins. Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mea |
Immunogen | n/a |
Other Names | [CK-16; CK16; cytokeratin 16; Cytokeratin-16; FNEPPK] |
Gene, Accession # | [CK16], Gene ID: 3868, NCBI: NP_005548.2, UniProt: P08779 |
Catalog # | MBS9400130 |
Price | $200, $255 |
Order / More Info | CK16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |