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Antigenic Specificity | CKII alpha Prime Polypeptide |
Clone | [5F9-H11-F7] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinasethat is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alphaand alpha' ) in a homomeric or heteromeric conformation. Whilst the alpha-and alpha'-subunits arecatalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to thealpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteinsimplicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thoughtto influence Wnt si |
Immunogen | Immunogen: Purified recombinant fragment of human CSNK2A2 (AA: 194-350) expressed in E. Coli. |
Other Names | [Casein kinase II subunit alpha'; Casein kinase II subunit alpha'; casein kinase II subunit alpha'; casein kinase 2 alpha 2] |
Gene, Accession # | [CSNK2A2], Gene ID: 1459, NCBI: P19784.1, UniProt: P19784 |
Catalog # | MBS8538952 |
Price | $280 |
Order / More Info | CKII alpha Prime Polypeptide Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |