CKII alpha Prime Polypeptide Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCKII alpha Prime Polypeptide
Clone[5F9-H11-F7]
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
Formatascites
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA)
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DescriptionCasein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinasethat is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alphaand alpha' ) in a homomeric or heteromeric conformation. Whilst the alpha-and alpha'-subunits arecatalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to thealpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteinsimplicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thoughtto influence Wnt si
ImmunogenImmunogen: Purified recombinant fragment of human CSNK2A2 (AA: 194-350) expressed in E. Coli.
Other Names[Casein kinase II subunit alpha'; Casein kinase II subunit alpha'; casein kinase II subunit alpha'; casein kinase 2 alpha 2]
Gene, Accession #[CSNK2A2], Gene ID: 1459, NCBI: P19784.1, UniProt: P19784
Catalog #MBS8538952
Price$280
Order / More InfoCKII alpha Prime Polypeptide Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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