Edit |   |
---|---|
Antigenic Specificity | MGME1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells. |
Immunogen | Immunogen: Recombinant human Mitochondrial genome maintenance exonuclease 1 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-85434 / sc-85435 |
Other Names | [Mitochondrial genome maintenance exonuclease 1UniRule annotation; MGME1], [MGME1; MGME1; DDK1; MTDPS11; C20orf72; bA504H3.4] |
Gene, Accession # | [MGME1], Gene ID: 92667, NCBI: NP_001297267.1, UniProt: Q9BQP7 |
Catalog # | MBS1491971 |
Price | $160, $235 |
Order / More Info | MGME1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |