CD3 zeta Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD3 zeta
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsRadioimmunoassay, Western Blot, Immunoprecipitation, Immunohistochemistry, Flow Cytometry
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DescriptionThis antibody recognizes human CD3 zeta protein. It cross-reacts to human, mouse and rat. The other species was not tested. CD3 is a glycoprotein consisting of up to five polypeptide chains (gp20, gp26, p16, p20, p28). It forms three dimmers: a heterodimer of gamma and epsilon chain, a heterodimer of delta and epsilon chains and a homodimer of two zeta chains or a heterodimer of zeta and eta chains. CD3 is required for proper assembly, trafficking and surface expression of TCR complex. CD3 is expressed by Thymocytes in a developmentally regulated manner and by all mature T cells. CD3 is involved in T cell activation, proliferation and apoptosis pathway. This protein is present on virtually all peripheral blood T cells and Thymocytes. The CD
ImmunogenAntigen Preparation: A synthetic peptide corresponding to the N-terminus of human CD3 zeta. This sequence is identical among human, rat and mouse species.
Other Names[Rabbit CD3; CD3 zeta], [LOC100305023]
Gene, Accession #[CD3 zeta], Gene ID: 100305023, NCBI: NP_001187191.1
Catalog #MBS462233
Price$285
Order / More InfoCD3 zeta Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKearse KP. Calnexin associates with monomeric and oligomeric (disulfidelinked) CD3delta proteins in murine T lymphocytes. J Biol Chem. (1998) 273 (23):141527.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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