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Antigenic Specificity | CD3 zeta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | Size: 100 ug/200 ul |
Applications | Radioimmunoassay, Western Blot, Immunoprecipitation, Immunohistochemistry, Flow Cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human CD3 zeta protein. It cross-reacts to human, mouse and rat. The other species was not tested. CD3 is a glycoprotein consisting of up to five polypeptide chains (gp20, gp26, p16, p20, p28). It forms three dimmers: a heterodimer of gamma and epsilon chain, a heterodimer of delta and epsilon chains and a homodimer of two zeta chains or a heterodimer of zeta and eta chains. CD3 is required for proper assembly, trafficking and surface expression of TCR complex. CD3 is expressed by Thymocytes in a developmentally regulated manner and by all mature T cells. CD3 is involved in T cell activation, proliferation and apoptosis pathway. This protein is present on virtually all peripheral blood T cells and Thymocytes. The CD |
Immunogen | Antigen Preparation: A synthetic peptide corresponding to the N-terminus of human CD3 zeta. This sequence is identical among human, rat and mouse species. |
Other Names | [Rabbit CD3; CD3 zeta], [LOC100305023] |
Gene, Accession # | [CD3 zeta], Gene ID: 100305023, NCBI: NP_001187191.1 |
Catalog # | MBS462233 |
Price | $285 |
Order / More Info | CD3 zeta Antibody from MYBIOSOURCE INC. |
Product Specific References | Kearse KP. Calnexin associates with monomeric and oligomeric (disulfidelinked) CD3delta proteins in murine T lymphocytes. J Biol Chem. (1998) 273 (23):141527. |