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Antigenic Specificity | AIRE (Isoform 1) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AIRE is a transcriptional regulator that is thought to be important in controlling tissue-specific expression of genes in the thymus. The precise function of the protein is not well defined. It contains zinc finger motifs. The AIRE isoform 1 (AIRE) is a splice variant and is localized to both the nucleus and cytoplasm. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). |
Immunogen | Immunogen: Purified, E Coli-derived, recombinant human Mothers Against DPP homolog 1 (rhSmad1; aa 2 - 454). |
Other Names | [autoimmune regulator; Autoimmune regulator; autoimmune regulator; autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein], [AIRE; AIRE; APS1; APSI; PGA1; AIRE1; APECED; APECED; APECED protein] |
Gene, Accession # | [AIRE], Gene ID: 326, NCBI: NP_000374.1, UniProt: O43918 |
Catalog # | MBS555904 |
Price | $440 |
Order / More Info | AIRE (Isoform 1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |