AIRE (Isoform 1) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAIRE (Isoform 1)
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionAIRE is a transcriptional regulator that is thought to be important in controlling tissue-specific expression of genes in the thymus. The precise function of the protein is not well defined. It contains zinc finger motifs. The AIRE isoform 1 (AIRE) is a splice variant and is localized to both the nucleus and cytoplasm. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
ImmunogenImmunogen: Purified, E Coli-derived, recombinant human Mothers Against DPP homolog 1 (rhSmad1; aa 2 - 454).
Other Names[autoimmune regulator; Autoimmune regulator; autoimmune regulator; autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein], [AIRE; AIRE; APS1; APSI; PGA1; AIRE1; APECED; APECED; APECED protein]
Gene, Accession #[AIRE], Gene ID: 326, NCBI: NP_000374.1, UniProt: O43918
Catalog #MBS555904
Price$440
Order / More InfoAIRE (Isoform 1) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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