AIF Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAIF
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionAIF Antibody: Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins. A novel gene, the product of which causes chromatin condensation and DNA fragmentation, was recently identified, cloned, and designated apoptosis inducing factor (AIF). Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and DNA fragmentation, whi
ImmunogenImmunogen: AIF antibody was raised against a 14 amino acid peptide near the carboxy terminus of human AIF. Buffer: AIF Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[AIF; CNK; KSR; CNK1; Connector enhancer of kinase suppressor of ras 1; CNK homolog protein 1; Connector enhancer of KSR 1; connector enhancer of kinase suppressor of Ras 1], [CNKSR1; CNKSR1; CNK; CNK1; CNK1; Connector enhancer of KSR 1; CNK1; hCNK1]
Gene, Accession #[CNKSR1], Gene ID: 10256, NCBI: Q969H4.1, UniProt: O95381
Catalog #MBS150089
Price$375
Order / More InfoAIF Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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