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Antigenic Specificity | PHC2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. This gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Immunogen | Immunogen: Rabbit polyclonal PHC2 (1) antibody was raised against a recombinate human PHC2 protein 553-835aa (BC029269). |
Other Names | [PHC2 protein; Polyhomeotic-like protein 2; polyhomeotic-like protein 2; early development regulator 2 (homolog of polyhomeotic 2); early development regulatory protein 2; polyhomeotic-like 2; polyhomeotic homolog 2 (Drosophila); Early development regulatory protein 2], [PHC2; PHC2; PH2; EDR2; HPH2] |
Gene, Accession # | [PHC2], Gene ID: 1912, NCBI: AAI44122.1 |
Catalog # | MBS416385 |
Price | $230 |
Order / More Info | PHC2 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Wu,H., Lin,Y., Shi,Y. et al. SIAH-1 interacts with mammalian polyhomeotic homologues HPH2 and affects its stability via the ubiquitin-proteasome pathway. Biochem. Biophys. Res. Commun. 397 (3), 391-396 (2010). |