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Antigenic Specificity | Human MAP2K1 / MEK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Xenopus, human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MEK1, a MAP2K type protein kinase, is a member of the Ras MAPK pathway. This pathway modulates the activity of transcription factors, structural proteins and other protein kinases, leading to biological responses such as cell proliferation and differentiation. MEK1 contains a proline-rich segment that is recognized by the scaffold protein MEK binding partner-1 (MP1). MP1 associates with non-phosphorylated MEK1, forming a complex which associates with and phosphorylates MAP kinases ERK1 and 2. |
Immunogen | Immunogen Description: Synthetic peptide derived from sequence near the amino-terminus of human MEK1, conjugated to KLH. |
Other Names | [MAP2K1 / MEK1 (N-Terminus) IHC-plus; MAP2K1; ERK activator kinase 1; MAPK/ERK kinase 1; MAPKK 1; MKK1; PRKMK1; MEK 1; MAP kinase kinase 1; MAPKK1; MEK1; Human MAP2K1; MEK1], [MEK1] |
Gene, Accession # | [MAP2K1], Gene ID: 5604, NCBI: NP_002746.1, UniProt: Q02750 |
Catalog # | MBS242684 |
Price | $530 |
Order / More Info | Human MAP2K1 / MEK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |