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Antigenic Specificity | UCN3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.6mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total UCN3 protein. This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite. |
Immunogen | Immunogen: Synthetic peptide corresponding to internal residues of human UCN3 Immunogen Type: Peptide |
Other Names | [SCP; SPC; UCNIII] |
Gene, Accession # | [UCN3], Gene ID: 114131, NCBI: NP_444277, UniProt: Q969E3 |
Catalog # | MBS9429841 |
Price | $255 |
Order / More Info | UCN3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |