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Antigenic Specificity | TRAF2 (C-term), 343-372 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TRAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the C-terminal region of human TRAF2. TRAF2 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction o |
Immunogen | n/a |
Other Names | [TNF receptor-associated factor 2; 632-; E3 ubiquitin-protein ligase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3; TRAF2; TRAP3] |
Gene, Accession # | [TRAF2], Gene ID: 7186, NCBI: NP_066961.2, UniProt: Q12933 |
Catalog # | MBS9212582 |
Price | $165, $370 |
Order / More Info | TRAF2 (C-term), 343-372 Antibody from MYBIOSOURCE INC. |
Product Specific References | Merluzzi,S., Mol. Immunol. 45 (1), 76-86 (2008) Mainou,B.A., J. Virol. 81 (18), 9680-9692 (2007) Morrison,B.H., J. Biol. Chem. 282 (21), 15349-15356 (2007) |