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Antigenic Specificity | F8 |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | F8. coagulation factor VIII, procoagulant component. This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant |
Immunogen | Immunogen: Purified recombinant fragment of F8 expressed in E. Coli. |
Other Names | [AHF; F8B; F8C; HEMA; FVIII], [F8; F8; AHF; F8B; F8C; HEMA; FVIII; DXS1253E; F8C; AHF] |
Gene, Accession # | [F8], Gene ID: 2157, NCBI: NP_000123.1, UniProt: P00451 |
Catalog # | MBS850307 |
Price | $280 |
Order / More Info | F8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |