Phospho- JAK2 (pTyr 1007/1008) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho- JAK2 (pTyr 1007/1008) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | biotin conjugate |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This biotinylated antibody recognizes JAK2 with dual phosphorylated sites of Tyr1007/1008. It does not crossreact with non-phosphospecific peptide. The Janus tyrosine kinase family is consists of four members, JAK1, JAK2, JAK3 and Tyk2. Upon the cytokine ligand binding to its the receptors, the dimerization of the receptors occurs followed by phosphorylation of the receptors. The phosphorylation of receptors recruites the tyrosine kinase physically associated to the dimerized receptors, and the phosphorylate the kinase, thus activates the signal transducer and activator of thranscription (STAT1, 3, 5) and the other signal proteins |
| Immunogen | Antigen Preparation: A synthetic peptide surrounding to the epitope -EYYK- with dual phosphorylation sites at Tyr1008 and Tyr1009 of JAK2 from human, mouse and rat origins. |
| Other Names | [Rabbit Phospho-JAK2 (pY1007/1008); Biotinylated; Biotin-conjugated Rabbit phosphospecifici-Janus Kinase 2], [JAK2; JAK2; JTK10] |
| Gene, Accession # | [JAK2 (pY1007/Y1008) (Biotinylated)], Gene ID: 3717, NCBI: NP_004963.1, UniProt: O60674 |
| Catalog # | MBS462108 |
| Price | $285 |
| Order / More Info | Phospho- JAK2 (pTyr 1007/1008) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yogev,O., et al. SHP-2 regulates SOCS-1-mediated Janus kinase-2 ubiquitination/degradation downstream of the prolactin receptor. J. Biol. Chem. 278 (52), 52021-52031 (2003) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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