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Antigenic Specificity | GOT2 |
Clone | [6C6-C7-G7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]. UniPort Summary Function: Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatt |
Immunogen | Immunogen: Purified recombinant fragment of human GOT2 expressed in E Coli. Sequence Similarities: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. |
Other Names | [AATM_HUMAN; AL022787; Aspartate aminotransferase 2; Aspartate aminotransferase; Aspartate aminotransferase, mitochondrial; Aspartate transaminase 2; ASPATA; EC 2.6.1.1; FABP 1; FABP pm; FABP-1; FABPpm; Fatty acid binding protein; Fatty acid-binding protein; FLJ40994; Glutamate oxaloacetate transaminase 2; Glutamate oxaloacetate transaminase 2, mitochondrial; Glutamate oxaloacetate transaminase, mitochondrial; Glutamic oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2); Got 2; GOT2; KAT4; KATIV; kynurenine aminotransferase 4; Kynurenine aminotransferase IV; kynurenine--oxoglutarate transaminase 4; kynurenine--oxoglutarate transaminase IV; mAspAT; MGC102129; MGC115763; mitAAT; mitochondrial; Mitochondrial aspartate aminotransferase; OTTMUSP00000017748; Plasma membrane fatty acid binding protein; Plasma membrane-associated fatty acid-binding protein; Transaminase A], [KAT4; KATIV; KYAT4; mitAAT] |
Gene, Accession # | [GOT2], Gene ID: 2806, NCBI: NP_001273149.1, UniProt: P00505 |
Catalog # | MBS475978 |
Price | $335 |
Order / More Info | GOT2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |