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Antigenic Specificity | ABAT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [GABAT; NPD009; GABA-AT], [ABAT; ABAT; GABAT; NPD009; GABA-AT; GABAT; GABA-AT; GABA transaminase; GABA-T] |
Gene, Accession # | [ABAT], Gene ID: 18, NCBI: P80404.3, UniProt: P80404 |
Catalog # | MBS129841 |
Price | $200, $275, $430 |
Order / More Info | ABAT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |