Human CD8 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD8 |
| Clone | [4ARiv11] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 50 tests, 100 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | 4ARiv11 reacts with the 32 kDa a chain of CD8. This molecule is expressed on the T suppressor/cytotoxic cell population (which comprises about 1/3 of the peripheral blood T lymphocytes total population) and with most of thymocytes, as well as a subset of NK cells. CD8 expresses as either a heterodimer with the CD8b chain (CD8ab) or as a homodimer (CD8aa or CD8bb). CD8 acts as a co-receptor with MHC Class I restricted TCRs in antigen recognition. CD8 function is important for positive selection of MHC Class I restricted CD8+ T cells during T cell development.* Ratio of CD4 and CD8 is important for monitor of HIV infection. |
| Immunogen | n/a |
| Other Names | [CD8, partial; CD8; T-cell surface glycoprotein CD8 alpha chain; CD8a molecule; CD8] |
| Gene, Accession # | [CD8], Gene ID: 403158, NCBI: ABA55041.1 |
| Catalog # | MBS8500495 |
| Price | $280, $300 |
| Order / More Info | Human CD8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1.Engleman EG et al. (1981) J Exp Med 153: 193-198. 2.Haynes, B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30. 3.Parnes, JR. et al. (1989). Adv. Immunol. 44, 256-311. 4.Bikah G. et al. (1996). Science 274:1906. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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