IRS4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IRS4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: IRS4 antibody detects endogenous levels of total IRS4. Function: Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity, such as insulin receptor, IGF1R and FGFR1, and a complex network of intracellular signaling molecules containing SH2 domains. Involved in the IGF1R mitogenic signaling pathway. Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis. Interaction with GRB2 enhances insulin-stimulated mitogen-activated protein kinase activity. May be involved in nonreceptor tyrosine kinase signaling in myoblasts. Plays a pivotal role in the proliferation/differentiation of hepatoblastoma cell th |
| Immunogen | Immunogen: A synthesized peptide derived from human IRS4 Subcellular Location: Cell Membrane; Peripheral Membrane Protein; Cytoplasmic Side. Tissue Specificity: Expressed in myoblasts. Expressed in liver and hepatocellular carcinoma. Predicted Cross Reactivity: Bovine, Horse, Rabbit Similarity: Bovine (91%), Horse (80%), Rabbit (83%) |
| Other Names | [160 kDa phosphotyrosine protein; Insulin receptor substrate 4; IRS 4; PY160] |
| Gene, Accession # | [IRS4], Gene ID: 8471, NCBI: NP_003595.1, UniProt: O14654 |
| Catalog # | MBS9608280 |
| Price | $240, $280 |
| Order / More Info | IRS4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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