ZBTB17 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityZBTB17
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionTranscription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation. Represses RB1 transcription; this repression can be blocked by interaction with ZBTB49 isoform 3/ZNF509S1 (PubMed:25245946).
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 121-360 of human ZBTB17 (NP 003434.2).
Other Names[MIZ-1; ZNF60; ZNF151; pHZ-67]
Gene, Accession #[ZBTB17], Gene ID: 7709, NCBI: NP_001229813.1, UniProt: Q13105
Catalog #MBS8547451
Price$280
Order / More InfoZBTB17 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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