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Antigenic Specificity | NUP98 |
Clone | [3B8-D7-H10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cel |
Immunogen | Immunogen: Purified recombinant human NUP98 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of NUP98 and does not cross-react with related proteins. Sequence Similarities: Belongs to the nucleoporin GLFG family. Contains 1 peptidase S59 domain. |
Other Names | [96 kDa nucleoporin; 98 kDa nucleoporin; ADAR2; ADIR2; GLFG-repeat containing nucleoporin; Nuclear pore complex protein Nup96; Nuclear pore complex protein Nup98 Nup96; Nucleoporin 98kD; nucleoporin 98kDa; Nucleoporin Nup96; Nucleoporin Nup98; NUP196; NUP96; Nup98; Nup98-Nup96; NUP98_HUMAN], [ADIR2; NUP96; NUP196] |
Gene, Accession # | [NUP98], Gene ID: 4928, NCBI: NP_005378.4, UniProt: P52948 |
Catalog # | MBS475002 |
Price | $335 |
Order / More Info | NUP98 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |