CXXC5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CXXC5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CXXC5 antibody detects endogenous levels of CXXC5. Function: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) (PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788).Subunit Structure: Interacts with DVL1. Interacts with RBPJ (PubMed:2330 |
| Immunogen | Immunogen: A synthesized peptide derived from human CXXC5. Subcellular Location: Nucleus. Cytoplasm. Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane. Tissue Specificity: By retinoic acid. Predicted Cross Reactivity: Pig, Bovine, Horse, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Dog (100%), Chicken (83%) |
| Other Names | [CF5; CXXC finger 5 protein; CXXC finger protein 5; CXXC-type zinc finger protein 5; CXXC5; CXXC5_HUMAN; HSPC195; Putative MAPK-activating protein PM08; Putative NF-kappa-B-activating protein 102; retinoid-inducible nuclear factor; RINF; TCCCIA00297; WID; WT1-induced Inhibitor of Dishevelled] |
| Gene, Accession # | [CXXC5], Gene ID: 51523, NCBI: NP_001304128.1, UniProt: Q7LFL8 |
| Catalog # | MBS9603606 |
| Price | $240, $280 |
| Order / More Info | CXXC5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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