Edit |   |
---|---|
Antigenic Specificity | SOCS3 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SOCS3 is an SH2-containing protein that binds to the activation loop of Janus kinases, inhibiting kinase activity and thereby suppressing cytokine signaling. It is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. The expression of the SOCS3 gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. Studies of the mouse counterpart of the SOCS3 gene suggested this gene is involved in the negative regulation of fetal liver hematopoiesis, and placental development. |
Immunogen | Immunogen: Recombinant fragment of Human SOCS3 (N-terminus). Preservative: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4. |
Other Names | [Mouse IgG to SOCS3], [SOCS3; SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3; CIS3; SSI3; SOCS-3; CIS-3; SSI-3] |
Gene, Accession # | [SOCS3], Gene ID: 9021, NCBI: NP_003946.3, UniProt: O14543 |
Catalog # | MBS850338 |
Price | $215, $280 |
Order / More Info | SOCS3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |