HLA-DRA (MHC II) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HLA-DRA (MHC II) |
| Clone | [IPO-10] |
| Host Species | Mouse |
| Reactive Species | human, monkey |
| Isotype | IgG3, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MAb IPO-10 defines the antigen, which appears on B cell progenitors following HLA-DR and preceding CD10, CD19, CD22, CD37 and cym. It is expressed on resting B cells and than reappears and persists in cytoplasm and on cell surface until cytoplasmic Ig appears. It is a useful antibody for diagnostics of neoplasms of B cell origins. It reacts with human B cell lines Daudi, Raji, Namalva, EB-3, RPMI-8226 (50% of cells). The MAb does not label T cell lines, blood granulocytes, thymocytes or bone marrow stromal fibroblasts. No significant changes are detected after PHA or ConA stimulation while LPS and PWM stimulated cultures after 18-48h show decreased number of antigen-positive cells but in final terms of cultivation antigen is ex |
| Immunogen | Immunogen: Spleen cells of a patient with hairy cell leukemia (Daudi cells) |
| Other Names | [DR alpha chain; HLA class II histocompatibility antigen; HLA class II histocompatibility antigen DR alpha chain; HLA DRA; HLA DRA1; HLA-DRA; HLADRA1; Major histocompatibility complex class II DR alpha; MHC cell surface glycoprotein; MHC class II antigen DRA], [HLA-DRA; HLA-DRA; MLRW; HLA-DRA1; HLA-DRA1] |
| Gene, Accession # | [HLA-DRA], Gene ID: 3122, NCBI: NP_061984.2, UniProt: P01903 |
| Catalog # | MBS438171 |
| Price | $190, $340, $340 |
| Order / More Info | HLA-DRA (MHC II) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Pinchouk V.G. et al., Monoclonal antibodies IPO-3 and IPO-10 against human B cell differentiation antigens. Anticancer Research 8, 1377-1380, 1988. Gluzman D.F. et al., Monoclonal antibodies IPO-3, IPO-4 and IPO-10 against lymphocyte differentiation antigens. Tissue Antigens 33, 151, 1989. Sidorenko S.P. et al., Monoclonal antibodies of IPO series against B cell differentiation antigens in leukemia and lymphoma immunophenotyping. Neoplasma 39, 3-9, 1992 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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