Cleaved-PARP-1 (G215) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCleaved-PARP-1 (G215)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Cleaved-PARP-1 (G215) Polyclonal Antibody detects endogenous levels of fragment of activated PARP-1 protein resulting from cleavage adjacent to G215. PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, poly(ADP-ribose) polymerase 1 may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
ImmunogenImmunogen: Synthesized peptide derived from the internal region of human PARP-1 at AA range: 170-250
Other Names[Rabbit Cleaved-PARP-1 (G215); PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1]
Gene, Accession #[PARP-1], Gene ID: 142, NCBI: NP_001609.2, UniProt: P09874
Catalog #MBS9700827
Price$130, $220, $325
Order / More InfoCleaved-PARP-1 (G215) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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